Биотехнологический способ получения меченого стабильными изотопами липид-транспортирующего белка чечевицы (Lens culinaris)
Липид-транспортирующие белки растений в диагностике и терапии аллергических заболеваний. Создание гипоаллергенных аналогов LTP, перспективы вакцинации. Химическая трансформация клеток E.coli. Расщепление гибридного белка, масс-спектрометрический анализ.
| Рубрика | Биология и естествознание |
| Вид | дипломная работа |
| Язык | русский |
| Дата добавления | 16.07.2013 |
| Размер файла | 1,8 M |
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5. Mrinal Bhavel, Dinesh Raj Methuku1. Small cysteine-rich proteins from plants: a rich resource of antimicrobial agents. // 2011, Science against microbial pathogens: communicating current research and technological advances A. Mйndez-Vilas (Ed.), pp.: 1074-1083.
6. Freddy Boutrot, Nathalie Chantret and Marie-Franзoise Gautier Genome-wide analysis of the rice and arabidopsis non-specific lipid transfer protein (nsLtp) gene families and identification of wheat nsLtp genes by EST data mining. // 2008, BMC Genomics, Vol. 9, N. 86, pp.: 1-19.
7. E.A. Rogozhin, T. I. Odintsova, A. Kh. Musolyamov, A. N. Smirnov, A. V. Babakov Ts. A., E.V. Grishin. The purification and characterization of a novel lipid transfer protein from caryopsis of barnyard grass (Echinochloa crusgalli). // 2009, Prikl Biokhim Mikrobiol., Vol. 45, N. 4, pp.: 363-368.
8. Laurian Zuidmeer-Jongejanet, Montserrat Fernandez- Rivas, Lars K PoulsenAngela Neubauer, Juan Asturias, Lars Blom, Joyce Boye, Carsten Bindslev-Jensen, Michael Clausen, Rosa Ferrara, Paula Garosi, Hans Huber, Bettina M Jensen, Stef Koppelman, Marek L Kowalski, Anna Lewandowska -Polak, Birgit Linhart, Bernard Maillere, Adriano Mari, Alberto Martinez, Clare EN Mills, Claudio Nicoletti, Dirk-Jan Opstelten, Nikos G Papadopoulos, Antonio Portoles, Neil Rigby, Enrico Scala, Heidi J Schnoor, Sigurveig T Sig urdardottir G, Frank Stolz, Ines Swoboda, Rudolf Valenta Rob van den Hout, Serge A Versteeg, Marianne Witten, Ronald van Ree. FAST: towards safe and effective subcutaneous immunotherapy of persistent life-threatening food allergies. // 2012, Clinical and Translational Allergy, Vol. 2, N. 5.
9. O. Quercia, G. Zoccatelli, G. F. Stefanini, G. Mistrello, S. Amato, M. Bolla, F. Emiliani, R. Asero // Allergy to beer in LTP-se nsitized patients : beers are not all the same // 2012, Allergy, Vol. 67, pp.: 1186-1189.
10. Sofнa Sirvent, Oscar Palomares, Javier Cuesta-Herranz, Mayte Villalba, Rosalia Rodriguez. Analysis of the Structural and Immunological Stability of 2S Albumin, Nonspecific Lipid Transfer Protein, Profilin Allergens from Mustard Seeds. // 2012, J. Agric. Food Chem., Vol. 60, pp.: 6011? 6018.
11. Chaves P, Torres MJ, Aranda A, et al. Natural killer-dendritic cell interaction in lymphocyte responses in hypersensitivity reactions to betalactams. // 2010, Allergy, Vol. 65, pp.: 1600-1608.
12. E.A. Pastorello,M. Monza, V. Pravettoni, R. Longhi, P. Bonara, J. Scibilia, L. Primavesi, R. Scorza. Characterization of the T-Cell Epitopes of the Major Peach Allergen Pru p 3. // 2010, Int Arch Allergy Immunol., Vol. 153, pp.: 1-12.
13. Tordesillas L, Cuesta-Herranz J, Gonzalez-Munoz M, Pacios LF, Compes E, Garcia-Carrasco B, Sanchez-Monge R, Salcedo G, Diaz-Perales A: T-cell epitopes of the major peach allergen, Pru p 3: identification and differential T-cell response of peach-allergic and non-allergic subjects. // 2009, Mol Immunol., Vol. 46, pp.: 722-728.
14. Schulten V, Radakovics A, Hartz C, Mari A, Vazquez-Cortes S, Fernandez-Rivas M, Lauer I, Jahn-Schmid B, Eiwegger T, Scheurer S, Bohle B: Characterization of the allergic T-cell response to Pru p 3, the nonspecific lipid transfer protein in peach. // 2009, J Allergy Clin Immunol., Vol. 124pp.: 100-107.
15. Enrique Gomez, Araceli Diaz-Perales, Leticia Tordesillas, Inmaculada Dooa, Maria J. Torres, Ana B. Blazquez, Francisca Gomez, Miguel Blanca, Cristobalina Mayorga. Effect of Pru p 3 on dendritic cell maturation and T-lymphocyte proliferation peach allergic patients. // 2012, Allergy Asthma Immunol., Vol. 109, pp.: 52-58.
16. Akdis CA, Akdis M. Mechanisms of allergen-specific immunotherapy. // 2011, J Allergy Clin Immunol., Vol. 127, pp.: 18-27.
17. Wambre E, Delong JH, James EA, Lafond RE, Robinson D, Kwok WW. Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy. // 2012, J Allergy Clin Immunol., Vol. 129, pp.: 544-551.
18. Valeria Cavatorta, Stefano Sforza, Giancarlo Aquino, Gianni Galaverna, Arnaldo Dossena, Elide Anna Pastorello, Rosangela Marchelli. In vitro gastrointestinal digestion of the major peach allergen Pru p 3, a lipid transfer protein: Molecular characterization of the products and assessment of their IgE binding abilities. // 2010, Mol. Nutr. Food Res, Vol. 54, pp.: 1452-1457.
19. J. M. Rolland, R. E. O'Hehir. Latex allergy: a model for therapy. // 2008, Clinical and Experimental Allergy, Vol. 38, pp.: 898-912.
20. R Asero. Lipid Transfer Protein Cross-reactivity Assessed In Vivo and In Vitro in the Office: Pros and Cons. // 2011, J Investig Allergol Clin Immunol., Vol. 21, N. 2, pp.: 129-136.
21. S. Denery-Papini, M. Bodinier, F. Pineau, S. Triballeau, O. Tranquet, K. Adel-Patient, D.A. Moneret-Vautrin, B. Bakan, D. Marion, T. Mothes, H. Mameri, D. Kasarda. Immunoglobulin-E-binding epitopes of wheat allergens in patients with food allergy to wheat and in mice experimentally sensitized to wheat proteins. // 2011, Clinical & Experimental Allergy, Vol. 41, pp.: 1478-1492.
22. Christina Hartz, Iris Lauer, Maria del Mar, San Miguel Moncin, Anna Cistero-Bahima, Kay Foetisch, Jonas Lidholm, Stefan Vieths, Stephan Scheurer. Comparison of IgE-Binding Capacity, Cross-Reactivity and Biological Potency of Allergenic Non-Specific Lipid Transfer Proteins from Peach, Cherry and Hazelnut. // 2010, Int Arch Allergy Immunol., Vol. 153, pp.: 335-346.
23. V. Schulten, B. Nagl, E. Scala, M. L. Bernardi, A. Mari, M. A. Ciardiello, I. Lauer, S. Scheurer, P. Briza, A.Jurets, F. Ferreira, B. Jahn-Schmid, G. F. Fischer, B. Bohle. Pru p 3, the nonspecific lipid transfer protein from peach, dominates the immune response to its homolog in hazelnut. // 2011, Allergy, 66, pp.: 1005-1013.
24. Leckie MJ, ten Brinke A, Khan J, Diamant Z, Okonnor BJ, Walls CM, et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response. // 2000, Lancet, Vol. 356, pp.: 2144-2148.
25. Garcia-Casado G, Crepo JF, Rodriguez J, Salcedo G. Isolation and characterization of barley lipid transfer protein and protein Zas beer allergens. // 2001, J Allergy Clin Immunol, Vol. 108, pp.: 647-649.
26. П.В. Колхир, Л.В. Лусс, И.В. Андреев. Пищевые аллергены: классификация и характеристика. // 2006, Аллергология и иммунология, Т. 7. - С. 276.
27. Martin D. Chapman. Allergen Nomenclature. // 2004, Indoor Biotechnologies, - P.12.
28. П.В. Колхир, Л.В. Лусс, И.В. Андреев. Пищевые аллергены: классификация и характеристика. // 2006, Аллергология и иммунология, Т. 7. - С. 276.
29. Jenkins J. A., Griffiths-Jones S., Shewry P. R., Breiteneder H., Mills E. N. Structural relatedness of plant food allergens with specific reference to cross-reactive allergens: An in silico analysis. // 2005, J Allergy Clin Immunol, Vol. 115 N. 1, pp. 163 -170.
30. Chapman MD, Smith AM, Vailes LD, et al. Recombinant allergens for diagnosis and therapy of allergic disease. // 2000, J Allergy Clin Immunol, Vol. 106, N. 3, pp. 409-418.
31. Aalberse RC. Structural biology of allergens. // 2000, J Allergy Clin Immunol, Vol. 106, N. 2, pp. 228-238.
32. Larche M, Akdis C A, Valenta R. Immunological mechanisms of allergen-specific immunotherapy. // 2006, Nat Rev Immunol, Vol. 6, pp.: 761-771.
33. Radauer C., Willerroider M., Fuchs H. Cross-reactive and species-specific immunoglobulin E epitopes of plant profilins: an experimental and structure-based analysis. // 2006, Clin Exp Allergy, Vol. 36, N. 7, pp. 920-929.
34. Pene J., Rousset F., Briere F., Chretien et al. IgE production by normal human B cells induced by alloreactive T cell clones is mediated by IL-4 and suppressed by IFN-gamma. // 1988, J. Immunol., Vol. 141, pp.: 1218-1224.
35. Punnonen J., Aversa G., Cocks B. G., McKenzie A. N., et al. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. // 1993, Proc. Natl. Acad. Sci. USA, Vol. 90, pp.: 3730-3734.
36. Breiteneder H, Radauer C. A classification of plant food allergens. // 2004, J Allergy Clin Immunol, Vol. 113, N. 5, pp. 821-830.
37. Vieths S, Scheurer S, Ballmer-Weber B. Current understanding of cross-reactivity of food allergens and pollen. // 2002, Ann N Y Acad Sci, Vol. 964, pp. 47-68.
38. Cevdet Ozdemir, Mubeccel Akdis, Cezmi A. Akdis. T-Cell Response to Allergens. // 2010, Chem Immunol Allergy. Basel, Karger, Vol 95, pp.: 22-44.
39. Mathur M, Herrmann K, Li X, Qin Y, Weinstock J, Elliott D, et al. TRFK-5 reverses established airway eosinophilia but not established hyperresponsiveness in a murine model of chronic asthma. // 1999, Am J Respir Crit Care Med, Vol.159, pp.: 580-587.
40. Leckie MJ, ten Brinke A, Khan J, Diamant Z, Okonnor BJ, Walls CM, et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperresponsiveness, and the late asthmatic response. // 2000, Lancet, Vol. 356, pp.: 2144-2148.
41. Martin D. Chapman. Allergen Nomenclature. // 2004, Indoor Biotechnologies, - P.12.
42. П.В. Колхир, Л.В. Лусс, И.В. Андреев. Пищевые аллергены: классификация и характеристика. // 2006, Аллергология и иммунология, Т. 7. - С. 276.
43. Jenkins J. A., Griffiths-Jones S., Shewry P. R., Breiteneder H., Mills E. N. Structural relatedness of plant food allergens with specific reference to cross-reactive allergens: An in silico analysis. // 2005, J Allergy Clin Immunol, Vol. 115 N. 1, pp. 163 -170.
44. Chapman MD, Smith AM, Vailes LD, et al. Recombinant allergens for diagnosis and therapy of allergic disease. // 2000, J Allergy Clin Immunol, Vol. 106, N. 3, pp. 409-418.
45. Aalberse RC. Structural biology of allergens. // 2000, J Allergy Clin Immunol, Vol. 106, N. 2, pp. 228-238.
46. Radauer C, Breiteneder H. Pollen allergens are restricted to few protein families and show distinct patterns of species distribution. // 2006, J Allergy Clin Immunol, Vol. 117, N. 1, pp. 141-147.
47. Radauer C., Willerroider M., Fuchs H. Cross-reactive and species-specific immunoglobulin E epitopes of plant profilins: an experimental and structure-based analysis. // 2006, Clin Exp Allergy, Vol. 36, N. 7, pp. 920-929.
48. Gadermaier G, Dedic A, Obermeyer G, et al. Biology of weed pollen allergens. // 2004, Curr Allergy Asthma Rep, Vol. 4, N. 5, pp. 391-400.
49. Gershoni J. M., Roitburd-Berman A., Siman-Tov D. D., Tarnovitski Freund N., Weiss Y. "Epitope mapping of allergen ovalbumin using biofunctionalized magnetic beads packed in microfluidic channels: The first step towards epitope-based vaccines". // 2007, BioDrugs, Vol. 21, N. 3, pp. 145-156.
50. Breiteneder H, Radauer C. A classification of plant food allergens. // 2004, J Allergy Clin Immunol, Vol. 113, N. 5, pp. 821-830.
51. Vieths S, Scheurer S, Ballmer-Weber B. Current understanding of cross-reactivity of food allergens and pollen. // 2002, Ann N Y Acad Sci, Vol. 964, pp. 47-68.
52. Cevdet Ozdemir, Mubeccel Akdis, Cezmi A. Akdis. T-Cell Response to Allergens. // 2010, Chem Immunol Allergy. Basel, Karger, Vol 95, pp.: 22-44.
53. John A. Jenkins, Sam Griffiths-Jones, Peter R. Shewry, Heimo Breiteneder, and E.N. Clare Mills. Structural relatedness of plant food allergens with specific reference to cross-reactive allergens: An in silico analysis. // 2005, J Allergy Clin Immunol, Vol. 115, pp. 163-170.
54. Asero R, Mistrello G, Roncarolo D, Amato S, Caldironi G, Barocci F, van Ree R. Immunological cross-reactivity between lipid transfer proteins from botanically unrelated plant-derived foods: a clinical study. // 2002, Allergy, Vol. 57, pp.: 900-906.
55. Diaz-Perales A, Lombardero M, Sanchez-Monge R, Garcia-Selles FJ, Pernas M, Fernandez-Rivas M, Barber D, Salcedo G. // 2000, Lipid-transfer proteins as potential plant panallergens: cross-reactivity among proteins of Artemisia pollen, Castanea nut and Rosaceae fruits, with different IgE-binding capacities. Clin Exp Allergy, Vol. 30, pp.: 1403-1410.
56. Pastorello E.A., Robino A.M. Clinical role of lipid transfer proteins in food allergy. // 2004, Mol Nutr Food Res., Vol. 48, pp.: 356-362.
57. Zuidmeer L., van Ree R. Lipid transfer protein allergy: primary food allergy or pollen/food syndrome in some cases. // 2007, Curr Opin Allergy Clin Immunol., Vol. 7, pp.: 269-273.
58. Werfel T., Ahlers G., Schmidt P., Boeker M., et al. Milk-responsive atopic dermatitis is associated with a casein-specific lymphocyte response in adolescent and adult patients. // 1997, J. Allergy Clin. Immunol., Vol. 99, pp.: 124-133.
59. Barbara Bohle. T lymphocytes and food allergy. // 2004, Mol. Nutr. Food Res., Vol. 48, pp.: 424 433.
60. Pastorello E.A., Pravettoni V., Farioli L., Rivolta F., Conti A., Ispano M., Fortunato D., Bengtsson A., Bianchi M. Hypersensitivity to mugwort (Artemisia vulgaris) in patients with peach allergy is due to a common lipid transfer protein allergen and is often without clinical expression. // 2002, J Allergy Clin Immunol., Vol. 110, pp. 310-317.
61. Martin D. Chapman. Allergen Nomenclature. // 2004, Indoor Biotechnologies, - P.12.
62. Asero R., Pravettoni V. Anaphylaxis to plant-foods and pollen allergens in patients with lipid transfer protein syndrome. // 2013, Curr Opin Allergy Clin Immunol.
63. Akdis M. Healthy immune response to allergens: T regulatory cells and more. // 2006, Curr Opin Immunol., Vol.18, pp.: 738-744.
64. Larche M, Akdis CA, Valenta R. Immunological mechanisms of allergen-specific immunotherapy. // 2006, Nat Rev Immunol., Vol. 6, pp.: 761-771.
65. Wang M, Takeda K, Shiraishi Y, Okamoto M, Dakhama A, Joetham A. Peanut-induced intestinal allergy is mediated through a mast cell-IgE-FcepsilonR I-IL-13 pathway. // 2010, J Allergy Clin Immunol., Vol.26, pp.: 306-316.
66. Cezmi A. Akdis, Mubeccel Akdis. Mechanisms of allergen-specific immunotherapy. // 2011, J Allergy Clin Immunol., Vol. 127, pp.: 18-27.
67. Romagnani S. Immunologic influences on allergy and the Th1/Th2 balance. // 2004, J Allergy Clin Immunol, Vol. 113, pp.: 395-400.
68. Burgler S., Ouaked N., Bassin C., Basinski T.M., Mantel P.Y., Siegmund K.Differenti ation and functional analysis of human Th17 cells. // 2009, J Allergy Clin Immunol., Vol. 123, pp.: 588-595.
69. van Hage-Hamsten M., Kronqvist M., Zetterstrom O., Johansson E., Niederberger V., Vrtala S. Skin test evaluation of genetically engineered hypoallergenic derivatives of the major birch pollen allergen, Bet v 1: results obtained with a mix of two recombinant Bet v 1 fragments and recombinant Bet v 1 trimer in a Swedish population before the birch pollen season. // 1999, J Allergy Clin Immunol., Vol. 104, pp.: 969-977.
70. Purohit A., Niederberger V., Kronqvist M., Horak F., Gronneberg R., Suck R. Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives. // 2008, Clin Exp Allergy, Vol. 38, pp.: 1514-1525.
71. Pree I., Shamji M.H., Kimber I., Valenta R., Durham S.R., Niederberger V. Inhibition of CD23-dependent facilitated allergen binding to B cells following vaccination with genetically modified hypoallergenic Bet v 1 molecules. // 2010, Clin Exp Allergy, Vol. 40, pp.: 1346-1352.
72. Pacios, L.F., Tordesillas, L., Cuesta-Herranz, J., Compes, E., Sanchez-Monge, R., Palacin, A., Salcedo, G., Diaz-Perales, A., 2008. Mimotope mapping as a complementary strategy to define allergen IgE-epitopes: peach Pru p 3 allergen as a model. Mol. Immunol., Vol. 45, pp.: 2269-2276.
73. Tang Q, Bluestone JA.The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. // 2008, Nat Immunol., Vol. 9, N. 3, pp.: 239-244.
74. Birgit Linhart, Rudolf Valenta. Vaccines for allergy. // 2012, Current Opinion in Immunology, Vol. 24, pp.: 354 - 360.
75. Heimo Breiteneder and Clare Mills. Structural bioinformatic approaches to understand cross-reactivity. // 2006, Mol. Nutr. Food Res., vol. 50, pp. 628-632.
76. Dardalhon V., Awasthi A., Kwon H., Galileos G., Gao W., Sobel R.A. IL-4 inhibits TGF -beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9 1 IL-101 Foxp3-effector T cells. // 2008, Nat Immunol., Vol. 9, pp.: 1347-1355.
77. Veldhoen M., Uyttenhove C., van Snick J., Helmby H., Westendorf A., Buer J. Transforming growth factor-beta ``reprograms'' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. // 2008, Nat Immunol., Vol. 9, pp.: 1341-1346.
78. Fiers M.W., Kleter G.A., Nijland H., Peijnenburg A.A., Nap J.P., van Ham R.C.: Allermatch, webtool for the prediction of potential allergenicity according to current FAO/WHO Codex alimentarius guidelines. // 2004, BMC Bioinformatics, Vol. 5, pp.: 133.
79. Li K.B., Issac P., Krishnan A. Predicting allergenic proteins using wavelet transform // 2004, Bioinformatics, Vol. 20, N. 16, pp.: 2572-2578.
80. Takagi K., Teshima R., Sawada J. Determination of human linear IgE epitopes of Japanese cedar allergen Cry j 1. // 2005, Biol. Pharm. Bull., Vol. 28, N. 8, pp.: 1496-1499.
81. Rudolf Valenta, Verena Niederberger. Recombinant allergens for immunotherapy. // 2007, J Allergy Clin Immunol., Vol. 119, pp.: 826-830.
82. Leticia Tordesillas, Javier Cuesta-Herranz, Miguel Gonzalez-Munoz. T-cell epitopes of the major peach allergen, Pru p 3: Identification and differential T-cell response of peach-allergic and non-allergic subjects. // 2009, Molecular Immunology, Vol. 46, pp.: 722-728.
83. Turcanu V, Maleki SJ, Lack G. Characterization of lymphocyte responses to peanuts in normal children, peanut-allergic children, and allergic children who acquired tolerance to peanuts. // 2003, J Clin Invest, Vol. 11, pp.: 1065-1072.
84. Judith A. Woodfolk. T-cell responses to allergens. // 2007, J Allergy Clin Immunol, Vol. 119, Num. 2, pp.: 280-294.
85. Janet M. Davies, Robyn E. O'Hehir, Cenk Suphioglu. Use of phage display technology to investigate allergen-antibody interactions. // 2000, J Allergy Clin Immunol., Vol. 105, pp.: 1085-1092.
86. Leticia Tordesillas, Luis F. Pacios, Arancha Palacin, Santiago Quirce, Alicia Armentia, Domingo Barber, Gabriel Salcedo, Araceli Diaz-Perales. Molecular basis of allergen cross-reactivity: Non-specific lipid transfer proteins from wheat flour and peach fruit as models. // 2009, Molecular Immunology, Vol. 47, pp.: 534-540.
87. Garcia-Casado, G., Pacios, L.F., Diaz-Perales, A., Sanchez-Monge, R., Lombardero, M., Garcia-Selles, F.J., Polo, F., Barber, D., Salcedo, G. Identification of IgE-binding epitopes of the major peach allergen Pru p 3. // 2003, J. Allergy Clin. Immunol., Vol. 112, pp.: 599-605.
88. Pacios, L.F., Tordesillas, L., Cuesta-Herranz, J., Compes, E., Sanchez-Monge, R., Palacin, A., Salcedo, G., Diaz-Perales, A., 2008. Mimotope mapping as a complementary strategy to define allergen IgE-epitopes: peach Pru p 3 allergen as a model. Mol. Immunol., Vol. 45, pp.: 2269-2276.
89. Tang Q, Bluestone JA.The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. // 2008, Nat Immunol., Vol. 9, N. 3, pp.: 239-244.
90. Birgit Linhart, Rudolf Valenta. Vaccines for allergy. // 2012, Current Opinion in Immunology, Vol. 24, pp.: 354 - 360.
91. Heimo Breiteneder and Clare Mills. Structural bioinformatic approaches to understand cross-reactivity. // 2006, Mol. Nutr. Food Res., vol. 50, pp. 628-632.
92. Jean-Philippe Borges, Annick Barre, Raphael Culerrier. How reliable is the structural prediction of IgE-binding epitopes of allergens? The case study of plant lipid transfer proteins. // 2007, Biochimie, Vol. 89, pp.: 83-91.
93. Garcia-Casado G, Pacios LF, Diaz-Perales A, et al. Identification of IgE-binding epitopes of the major peach allergen Pru p 3. // 2003, J Allergy Clin Immunol, Vol. 112, pp.: 599-605.
94. Luis F. Pacios, Leticia Tordesillas, Javier Cuesta-Herranz, Esther Compes, Rosa Sanchez-Monge, Arantxa Palacin et al. Mimotope mapping as a complementary strategy to define allergen IgE-epitopes: Peach Pru p 3 allergen as a model. // 2008, Molecular Immunology, Vol. 45, pp.: 269-276.
95. G. Salcedo, R. Sanchez-Monge, D. Barber, A. Diaz-Perales. Plant non-specific lipid transfer proteins: An interface between plant defence and human allergy. // 2007, Biochimica et Biophysica Acta, Vol. 1771, pp.: 781-791.
96. Moreau P, Bessoule J, Mongrand S, Testet E, Vincent P, Cassagne C. Lipid trafficking in plant cells. // 1998, Prog Lipid Res, Vol. 37, p.3711.
97. De Palma R, Wu S, Sallusto F. Use of antagonist peptides to inhibit in vitro T cell responses to Par j 1, the major allergen of Parietaria judaica pollen. // 1999, J Immunol, Vol. 162, pp.: 1982-1987.
98. Leticia Tordesillas, Javier Cuesta-Herranz, Miguel Gonzalez-Munoz. T-cell epitopes of the major peach allergen, Pru p 3: Identification and differential T-cell response of peach-allergic and non-allergic subjects. // 2009, Molecular Immunology, Vol. 46, pp.: 722-728.
99. Veronique Schulten, Astrid Radakovics, Christina Hartz. Characterization of the allergic T-cell response to Pru p 3, the nonspecific lipid transfer protein in peach. // 2009, J. Allergy Clin Immunol., Vol. 124, N.1, pp.: 100-107.
100. Asero R. Plant Food Allergies: A Suggested Approach to Allergen-resolved Diagnosis in the Clinical Practice by Identifying Easily Available Sensitization Markers. // 2005, Int Arch Allergy Immunol., Vol. 138, pp.: 1-11.
101. Jutel M et al. Allergen-specific immunotherapy with recombinant grass pollen allergens. // 2005, J Allergy Clin Immunol, Vol. 116, pp.: 608-13.
102. R. Christopher Van Winkle, Christopher Chang. The Biochemical Basis and Clinical Evidence of Food Allergy Due to Lipid Transfer Proteins: A Comprehensive Review. // 2012, Clinic Rev Allerg Immunol.
103. Birgit Linhart, Rudolf Valenta. Mechanisms underlying allergy vaccination with recombinant hypoallergenic allergen derivatives. // 2012, Vaccine 30, pp.: 4328- 4335.
104. Greenhawt MJ. Oral and sublingual peanut immunotherapy is not ready for general use. // 2013, Allergy Asthma Proc., Vol. 34, N. 3, pp.: 197-204.
105. Yukselen A, Kendirli SG, Yilmaz M, Altintas DU, Karakoc GB. Effect of one-year subcutaneous and sublingual immunotherapy on clinical and laboratory parameters in children with rhinitis and asthma: a randomized, placebo-controlled, double-blind, double-dummy study. // 2012, Int Arch Allergy Immunol., Vol. 157, N. 3, pp.: 288-298.
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